منابع مشابه
Cleavage of pyrene-stabilized RNA bulge loops by trans-(±)-cyclohexane-1,2-diamine
Chemical agents that cleave HIV genome can be potentially used for anti-HIV therapy. In this report, the cleavage of the upper stem-loop region of HIV-1 TAR RNA was studied in a variety of buffers containing organic catalysts. trans-(±)-Cyclohexane-1,2-diamine was found to cleave the RNA with the highest activity (31%, 37°C, 18 h). Cleavage of the RNA in trans-(±)-cyclohexane-1,2-diamine buffer...
متن کاملIsomer formation in the binding of [PtCl2(cis-cyclohexane-1,3- diamine)] to oligonucleotides and the X-ray crystal structure of [PtCl2(cis-cyclohexane-1,3-diamine)] dimethylformamide†
The crystal structure of [PtCl2(cis-1,3-chxn)] (cis-1,3-chxn = (cis-cyclohexane-1,3-diamine)) as the dimethyformamide solvate is reported. When [PtCl2(cis-1,3-chxn)] binds to d(GpG), two isomers are formed that are readily separated by HPLC. Both the HPLC and GFAAS studies of the products show that the isomers form in a 1 : 1 ratio. Competition experiments involving d(GpG) and the aquated and n...
متن کاملtrans-Diaquabis(cyclohexane-1,2-diamine)zinc(II) dichloride
In the title compound, [Zn(C(6)H(14)N(2))(2)(H(2)O)(2)]Cl(2), the Zn(II) atom resides on a special position with site symmetry 2/m and is octa-hedrally coordinated by four N atoms from two trans 1,2-diamino-cyclo-hexane ligands and two water O atoms. In the crystal, N-H⋯Cl and O-H⋯Cl hydrogen bonds link the mol-ecules into a two-dimensional network parallel to the bc plane.
متن کاملtrans-Dichlorido(2,2-dimethylpropane-1,3-diamine)bis(triphenylphosphane)ruthenium(II)
In the title compound, [RuCl(2)(C(5)H(14)N(2))(C(18)H(15)P)(2)], the Ru(II) atom is six-coordinated, forming a slightly distorted octa-hedral geometry, with two chloride ions in an axial arrangement, and two P atoms of two triphenyl-phosphane and two chelating N atoms of the bidentate 2,2-dimethyl-propane-1,3-diamine ligand located in the equatorial plane. The average Ru-P, Ru-N and Ru-Cl bond ...
متن کاملModular synthesis of cyclic cis- and trans-1,2-diamine derivatives.
Structurally diverse carbocycles with two vicinal nitrogen-substituents were prepared in expedient three-component reactions from simple amines, aldehydes, and nitroalkenes. trans,trans-6-Nitrocyclohex-2-enyl amines were obtained in a one-pot domino reaction involving condensation, tautomerisation, conjugate addition, and nitro-Mannich cyclisation. Upon employment of less nucleophilic carboxami...
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ژورنال
عنوان ژورنال: Journal of Chemical Education
سال: 1999
ISSN: 0021-9584,1938-1328
DOI: 10.1021/ed076p1484.1